Novobiocin, ノボビオシン;

New Drug Approvals

Novobiocin

ノボビオシン;

• Molecular FormulaC₃₁H₃₆N₂O₁₁
• Average mass612.624 Da

(3R,4S,5R,6R)-5-hydroxy-6-(4-hydroxy-3-(4-hydroxy-3-(3-methylbut-2-enyl)benzamido)-8-methyl-2-oxo-2H-chromen-7-yloxy)-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate

(3R,4S,5R,6R)-5-Hydroxy-6-[(4-hydroxy-3-{[4-hydroxy-3-(3-methyl-2-buten-1-yl)benzoyl]amino}-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate (non-preferred name) [ACD/IUPAC Name]

(3R,4S,5R,6R)-5-Hydroxy-6-[(4-hydroxy-3-{[4-hydroxy-3-(3-methyl-2-buten-1-yl)benzoyl]amino}-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate (non-preferred name)

(3R,4S,5R,6R)-5-Hydroxy-6-[(4-hydroxy-3-{[4-hydroxy-3-(3-methylbut-2-en-1-yl)benzoyl]amino}-8-methyl-2-oxo-2H-chromen-7-yl)oxy]-3-methoxy-2,2-dimethyltetrahydro-2H-pyran-4-yl carbamate (non-preferred name)

1476-53-5 [RN]

17EC19951N

216-023-6 [EINECS]

224-321-2 [EINECS]

575

Albamycin[Trade name]

Biotexin

UNII17EC19951N

CAS number303-81-1

WeightAverage: 612.6243
Monoisotopic: 612.231910004

Chemical FormulaC₃₁H₃₆N₂O₁₁

For the treatment of infections due to staphylococci and other susceptible organisms

 Novobiocin

CAS Registry Number: 303-81-1

CAS Name: N-[7-[[3-O-(Aminocarbonyl)-6-deoxy-5-C-methyl-4-O-methyl-b-L-lyxo-hexopyranosyl]oxy]-4-hydroxy-8-methyl-2-oxo-2H-1-benzopyran-3-yl]-4-hydroxy-3-(3-methyl-2-butenyl)benzamide

Additional Names: crystallinic acid; streptonivicin

Manufacturers’ Codes: PA-93; U-6591

Molecular Formula: C31H36N2O11

Molecular Weight: 612.62

Percent Composition: C 60.78%, H 5.92%, N 4.57%, O 28.73%

Literature References: Antibiotic substance produced by Streptomyces spheroides: Kaczka et al., J. Am. Chem. Soc. 77, 6404 (1955); Wolf, US 3000873 (1961 to Merck &…

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